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Open Access
Peer-reviewed
Research Article
In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection
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Amanda L. Miller ,
Contributed equally to this work with: Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Aaron P. White, Çagla Tükel
Roles Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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J. Alex Pasternak ,
Contributed equally to this work with: Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Aaron P. White, Çagla Tükel
Roles Investigation, Methodology, Writing – review & editing
Current address: Department of Animal Sciences, Purdue University, 270 S. Russell St, West Lafayette, Indiana, United States of America
Affiliation Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada
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Nicole J. Medeiros ,
Contributed equally to this work with: Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Aaron P. White, Çagla Tükel
Roles Investigation, Methodology, Writing – original draft
Current address: Janssen Research & Development, LLC, Spring House, Pennsylvania, United States of America
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Lauren K. Nicastro,
Roles Investigation, Methodology
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Sarah A. Tursi,
Roles Investigation
Current address: Janssen Research & Development, LLC, Spring House, Pennsylvania, United States of America
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Elizabeth G. Hansen,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Ryan Krochak,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Akosiererem S. Sokaribo,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Keith D. MacKenzie,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Melissa B. Palmer,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Dakoda J. Herman,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Nikole L. Watson,
Roles Investigation
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Yi Zhang,
Roles Methodology, Supervision
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Heather L. Wilson,
Roles Supervision
Affiliation Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada
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R. Paul Wilson,
Roles Conceptualization, Methodology, Supervision, Validation
Current address: GlaxoSmithKline, Collegeville, Pennsylvania, United States of America
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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Aaron P. White ,
Contributed equally to this work with: Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Aaron P. White, Çagla Tükel
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: aaron.white@usask.ca (APW); ctukel@temple.edu (CT)
Affiliations Vaccine and Infectious Disease Organization-International Vaccine Centre, Saskatoon, Saskatchewan, Canada, Department of Biochemistry, Microbiology and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
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Çagla Tükel
Contributed equally to this work with: Amanda L. Miller, J. Alex Pasternak, Nicole J. Medeiros, Aaron P. White, Çagla Tükel
Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
* E-mail: aaron.white@usask.ca (APW); ctukel@temple.edu (CT)
Affiliation Department of Microbiology and Immunology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America
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In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection
- Amanda L. Miller,
- J. Alex Pasternak,
- Nicole J. Medeiros,
- Lauren K. Nicastro,
- Sarah A. Tursi,
- Elizabeth G. Hansen,
- Ryan Krochak,
- Akosiererem S. Sokaribo,
- Keith D. MacKenzie,
- Melissa B. Palmer
- Published: July 9, 2020
- https://doi.org/10.1371/journal.ppat.1008591