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Open Access
Peer-reviewed
Research Article
Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB
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Ruslana Bryk ,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
* E-mail: rub2001@med.cornell.edu
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Shashirekha Mundhra,
Roles Data curation, Formal analysis, Investigation
Affiliations Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America, Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America
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Xiuju Jiang,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Madeleine Wood,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Daniel Pfau,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Elaina Weber,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Suna Park,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Li Zhang,
Roles Investigation, Methodology
Affiliation Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America
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Colin Wilson,
Roles Data curation, Investigation, Resources
Affiliation Drug Discovery and Development Centre, H3D, University of Cape Town, Rondebosch, South Africa
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Renier Van der Westhuyzen,
Roles Investigation, Resources
Affiliation Drug Discovery and Development Centre, H3D, University of Cape Town, Rondebosch, South Africa
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Leslie Street,
Roles Methodology, Resources
Affiliation Drug Discovery and Development Centre, H3D, University of Cape Town, Rondebosch, South Africa
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Kelly Chibale,
Roles Resources
Affiliations Drug Discovery and Development Centre, H3D, University of Cape Town, Rondebosch, South Africa, South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry and Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Rondebosch, South Africa
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Matthew Zimmerman,
Roles Investigation
Affiliation Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, United States of America
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Véronique Dartois,
Roles Investigation, Methodology, Resources
Affiliation Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, United States of America
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Nunzia Pastore,
Roles Resources
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy
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Andrea Ballabio,
Roles Resources
Affiliations Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America, Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, Medical Genetics, Department of Medical and Translational Sciences, Federico II University, Naples, Italy, Ian and Dan Duncan Neurological Research Institute, Texas Children Hospital, Houston, Texas, United States of America
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Natalie Hawryluk,
Roles Data curation, Formal analysis, Investigation, Methodology, Resources
Affiliation Celgene Global Health, San Diego, California, United States of America
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Stacie Canan,
Roles Resources
Affiliation Celgene Global Health, San Diego, California, United States of America
⨯ - Vikram Khetani,
- Joseph Camardo,
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Carl Nathan
Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Writing – original draft
Affiliations Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York, United States of America, Immunology and Microbial Pathogenesis Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, United States of America
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Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB
- Ruslana Bryk,
- Shashirekha Mundhra,
- Xiuju Jiang,
- Madeleine Wood,
- Daniel Pfau,
- Elaina Weber,
- Suna Park,
- Li Zhang,
- Colin Wilson,
- Renier Van der Westhuyzen
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- Published: June 23, 2020
- https://doi.org/10.1371/journal.ppat.1008567