Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium

• Gregory A. Taylor ,

  Contributed equally to this work with: Gregory A. Taylor, Hsin-I Huang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gregory.taylor@duke.edu (GAT); gianna.hammer@duke.edu (GEH)

  Affiliations Geriatric Research, Education, and Clinical Center, VA Health Care Center, Durham, North Carolina, United States of America, Departments of Medicine, Division of Geriatrics, and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0003-1966-0917

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• Hsin-I Huang ,

  Contributed equally to this work with: Gregory A. Taylor, Hsin-I Huang

  Roles Data curation, Formal analysis

  Affiliation Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0001-9106-9449

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• Brian E. Fee,

  Roles Data curation, Formal analysis

  Affiliation Geriatric Research, Education, and Clinical Center, VA Health Care Center, Durham, North Carolina, United States of America

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• Nourhan Youssef,

  Roles Data curation, Formal analysis

  Affiliation Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

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• Mark L. Jewell,

  Roles Data curation, Formal analysis

  Affiliation Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0003-0128-2241

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• Viviana Cantillana,

  Roles Data curation, Formal analysis

  Affiliation Departments of Medicine, Division of Geriatrics, and Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, North Carolina, United States of America

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• Alexi A. Schoenborn,

  Roles Data curation, Formal analysis

  Affiliations Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Allison R. Rogala,

  Roles Data curation, Formal analysis

  Affiliations Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pediatrics, Division of Gastroenterology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Anne F. Buckley,

  Roles Data curation, Formal analysis

  Affiliation Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0003-1209-5791

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• Carl G. Feng,

  Roles Resources

  Affiliation Department of Infectious Diseases and Immunology, University of Sydney, Sydney, NSW, Australia

  http://orcid.org/0000-0003-4301-4640

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• Bruce A. Vallance,

  Roles Resources, Writing – review & editing

  Affiliation Department of Pediatrics, Division of Gastroenterology, BC Children’s Hospital Research Institute, Vancouver, British Columbia, Canada

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• Ajay S. Gulati,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – review & editing

  Affiliations Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Pediatrics, Division of Gastroenterology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-7612-6369

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• Gianna E. Hammer

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gregory.taylor@duke.edu (GAT); gianna.hammer@duke.edu (GEH)

  Affiliations Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

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