Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival

• Michael D. Schultz,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  ⨯
• Tulin Dadali,

  Roles Formal analysis, Methodology, Writing – review & editing

  Current address: Genocea Biosciences, Cambridge, Massachusetts, United States of America

  Affiliation Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  ⨯
• Sylvain A. Jacques,

  Roles Resources, Writing – review & editing

  Affiliation Laboratoire d’Innovation Thérapeutique, LIT UMR 7200 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France

  ⨯
• Hélène Muller-Steffner,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Laboratoire des Systèmes Chimiques Fonctionnels, CAMB UMR 7199 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France

  ⨯
• Jeremy B. Foote,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  ⨯
• Leonardo Sorci,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Materials, Environmental Sciences and Urban Planning, Division of Bioinformatics and Biochemistry, Polytechnic University of Marche, Ancona, Italy

  http://orcid.org/0000-0002-4356-8873

  ⨯
• Esther Kellenberger,

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Laboratoire d’Innovation Thérapeutique, LIT UMR 7200 CNRS-Université de Strasbourg, MEDALIS Drug Discovery Center, Faculté de Pharmacie, Illkirch, France

  http://orcid.org/0000-0002-9320-4840

  ⨯
• Davide Botta ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  ¶‡ These authors share last authorship on this work.

  Affiliation Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  http://orcid.org/0000-0003-3926-0662

  ⨯
• Frances E. Lund

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Writing – original draft, Writing – review & editing

  * E-mail: flund@uab.edu

  ¶‡ These authors share last authorship on this work.

  Affiliation Department of Microbiology, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America

  http://orcid.org/0000-0003-3083-1246

  ⨯