TLR4 abrogates the Th1 immune response through IRF1 and IFN-β to prevent immunopathology during L. infantum infection

• Laís Amorim Sacramento,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto

  http://orcid.org/0000-0003-1987-8369

  ⨯
• Luciana Benevides,

  Roles Methodology

  Affiliations Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Fiocruz-Bi-Institutional Translational Medicine Project, Brazil

  ⨯
• Sandra Regina Maruyama,

  Roles Formal analysis, Methodology

  Affiliation Center for Biological and Health Sciences, Federal University of São Carlos, São Carlos, Brazil

  http://orcid.org/0000-0001-6807-1452

  ⨯
• Lucas Tavares,

  Roles Methodology

  Affiliation Department of Cellular and Molecular Biology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil

  http://orcid.org/0000-0001-7883-1443

  ⨯
• Kiyoshi Ferreira Fukutani,

  Roles Methodology

  Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto

  http://orcid.org/0000-0003-2223-0918

  ⨯
• Marcela Francozo,

  Roles Methodology

  Affiliation Institute of Infection Immunology, Centre for Experimental and Clinical Infection Research (Twincore), Hannover Medical School (MHH) and Helmholtz Centre for Infection Research (HZI), Hannover, Germany

  ⨯
• Tim Sparwasser,

  Roles Resources

  Affiliations Institute of Infection Immunology, Centre for Experimental and Clinical Infection Research (Twincore), Hannover Medical School (MHH) and Helmholtz Centre for Infection Research (HZI), Hannover, Germany, Department of Medical Microbiology and Hygiene, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany

  ⨯
• Fernando Queiroz Cunha,

  Roles Funding acquisition, Resources

  Affiliation Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil

  http://orcid.org/0000-0003-4755-1670

  ⨯
• Roque Pacheco Almeida,

  Roles Resources

  Affiliation Center for Biology and Health Sciences, Federal University of Sergipe, Aracaju, SE, Brazil

  ⨯
• João Santana da Silva,

  Roles Funding acquisition, Resources

  Affiliations Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Fiocruz-Bi-Institutional Translational Medicine Project, Brazil

  http://orcid.org/0000-0002-3410-3927

  ⨯
• Vanessa Carregaro

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: vcarregaro@usp.br, vcarregaro@fmrp.usp.br

  Affiliation Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto

  http://orcid.org/0000-0002-8435-0766

  ⨯