Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation

• Weili Kong ,

  Contributed equally to this work with: Weili Kong, Ayan Biswas

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America, Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, United States of America

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• Ayan Biswas ,

  Contributed equally to this work with: Weili Kong, Ayan Biswas

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America

  ⨯
• Dawei Zhou,

  Roles Writing – review & editing

  Affiliation Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America

  ⨯
• Guillaume Fiches,

  Roles Writing – review & editing

  Affiliation Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America

  http://orcid.org/0000-0003-3515-8417

  ⨯
• Koh Fujinaga,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• Netty Santoso,

  Roles Resources, Writing – review & editing

  Affiliation Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America

  http://orcid.org/0000-0003-1175-5831

  ⨯
• Jian Zhu

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Jian.Zhu@osumc.edu

  Affiliation Department of Pathology, Ohio State University College of Medicine, Columbus, Ohio, United States of America

  http://orcid.org/0000-0001-9856-8320

  ⨯