Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

Anika Singanayagam; Jie Zhou; Ruth A. Elderfield; Rebecca Frise; Jonathan Ashcroft; Monica Galiano; Shahjahan Miah; Laura Nicolaou; Wendy S. Barclay

doi:10.1371/journal.ppat.1008362

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Open Access

Peer-reviewed

Research Article

Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

Anika Singanayagam,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom

http://orcid.org/0000-0002-2572-0173

⨯
Jie Zhou,

Roles Data curation

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom
⨯
Ruth A. Elderfield,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom
⨯
Rebecca Frise,

Roles Data curation

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom

http://orcid.org/0000-0002-5522-623X

⨯
Jonathan Ashcroft,

Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom

http://orcid.org/0000-0002-6224-4233

⨯
Monica Galiano,

Roles Data curation, Formal analysis

Affiliation Virus Reference Department, Public Health England, Colindale, United Kingdom
⨯
Shahjahan Miah,

Roles Data curation

Affiliation Virus Reference Department, Public Health England, Colindale, United Kingdom

http://orcid.org/0000-0001-7810-3497

⨯
Laura Nicolaou,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Department of Mechanical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Wendy S. Barclay

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: w.barclay@imperial.ac.uk

Affiliation Department of Medicine, St. Marys Campus, Imperial College, London, United Kingdom

http://orcid.org/0000-0002-3948-0895

⨯

Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

Anika Singanayagam,
Jie Zhou,
Ruth A. Elderfield,
Rebecca Frise,
Jonathan Ashcroft,
Monica Galiano,
Shahjahan Miah,
Laura Nicolaou,
Wendy S. Barclay

Published: February 25, 2020
https://doi.org/10.1371/journal.ppat.1008362

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