An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing

• Raymond W. Wong ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rw.wong@mail.utoronto.ca (RWW); alan.cochrane@utoronto.ca (AC)

  Affiliations Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

  http://orcid.org/0000-0001-9699-5062

  ⨯
• Ahalya Balachandran,

  Roles Formal analysis, Funding acquisition, Investigation, Methodology, Validation

  Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Peter K. Cheung,

  Roles Formal analysis, Investigation, Validation

  Affiliation British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada

  http://orcid.org/0000-0001-6520-7852

  ⨯
• Ran Cheng,

  Roles Investigation

  Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  http://orcid.org/0000-0001-5556-8531

  ⨯
• Qun Pan,

  Roles Formal analysis

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Peter Stoilov,

  Roles Investigation, Resources

  Affiliation Department of Biochemistry, West Virginia University, Morgantown, West Virginia, United States of America

  http://orcid.org/0000-0003-1108-7271

  ⨯
• P. Richard Harrigan,

  Roles Resources, Supervision

  Affiliations British Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada, Department of Medicine, The University of British Columbia, Vancouver, British Columbia, Canada

  ⨯
• Benjamin J. Blencowe,

  Roles Resources, Supervision

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Donald R. Branch,

  Roles Resources, Supervision

  Affiliations Department of Medicine, University of Toronto, Toronto, Ontario, Canada, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada, Division of Advanced Diagnostics, Infection and Immunity Group, Toronto General Hospital Research Institute, Toronto, Ontario, Canada, Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada

  http://orcid.org/0000-0002-8974-2451

  ⨯
• Alan Cochrane

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: rw.wong@mail.utoronto.ca (RWW); alan.cochrane@utoronto.ca (AC)

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada

  ⨯