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Open Access
Peer-reviewed
Research Article
The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis
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Thuy Hoang,
Roles Conceptualization, Formal analysis, Investigation, Resources, Software, Writing – original draft, Writing – review & editing
Affiliations The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Emily Toler,
Roles Formal analysis, Investigation, Software, Writing – review & editing
Affiliation The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Kevin DeLong,
Roles Formal analysis, Investigation, Software, Writing – review & editing
Affiliations The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Nomfuneko A. Mafunda,
Roles Investigation, Writing – review & editing
Affiliation Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Cambridge, Massachusetts, United States of America
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Seth M. Bloom,
Roles Investigation, Software, Writing – review & editing
Affiliations Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Cambridge, Massachusetts, United States of America, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Hannah C. Zierden,
Roles Investigation, Writing – review & editing
Affiliations The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America
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Thomas R. Moench,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America
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Jenell S. Coleman,
Roles Resources, Writing – review & editing
Affiliation Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Justin Hanes,
Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing
Affiliations The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, United States of America
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Douglas S. Kwon,
Roles Investigation, Resources, Software, Writing – review & editing
Affiliations Ragon Institute of MGH, MIT, and Harvard, Massachusetts General Hospital, Cambridge, Massachusetts, United States of America, Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
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Samuel K. Lai,
Roles Resources, Writing – review & editing
Affiliation Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, UNC/NCSU Joint Department of Biomedical Engineering, Department of Microbiology & Immunology, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, United States of America
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Richard A. Cone,
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
Affiliation Department of Biophysics, Johns Hopkins University, Baltimore, Maryland, United States of America
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Laura M. Ensign
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: lensign@jhmi.edu
Affiliations The Center for Nanomedicine, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Ophthalmology, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, United States of America
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The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis
- Thuy Hoang,
- Emily Toler,
- Kevin DeLong,
- Nomfuneko A. Mafunda,
- Seth M. Bloom,
- Hannah C. Zierden,
- Thomas R. Moench,
- Jenell S. Coleman,
- Justin Hanes,
- Douglas S. Kwon
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- Published: January 23, 2020
- https://doi.org/10.1371/journal.ppat.1008236