Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans

• Nelson R. Wu ,

  Contributed equally to this work with: Nelson R. Wu, Nathan I. Nicely

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0002-2612-8729

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• Nathan I. Nicely ,

  Contributed equally to this work with: Nelson R. Wu, Nathan I. Nicely

  Roles Conceptualization, Funding acquisition, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0002-0025-2377

  ⨯
• Esther M. Lee,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• Rachel K. Reed,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• Brian E. Watts,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• Fangping Cai,

  Roles Investigation

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• William E. Walkowicz,

  Roles Investigation, Resources

  Affiliation Department of Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

  http://orcid.org/0000-0002-7961-1175

  ⨯
• Baptiste Aussedat,

  Roles Investigation, Resources

  Affiliation Department of Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

  http://orcid.org/0000-0002-8828-8963

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• Julia A. Jones,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0002-4900-5406

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• Amanda Eaton,

  Roles Investigation, Project administration

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0003-3064-2947

  ⨯
• Ashley M. Trama,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• S. Munir Alam,

  Roles Formal analysis, Supervision, Validation

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Biomedical Engineering, Duke University Medical Center, Durham, North Carolina, United States of America

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• David C. Montefiori,

  Roles Supervision, Validation, Writing – review & editing

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0003-0856-6319

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• Barton F. Haynes,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

  ⨯
• Kevin O. Saunders

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: kevin.saunders@duke.edu

  Affiliations Duke Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

  http://orcid.org/0000-0001-7399-7954

  ⨯