14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases

Soham Gupta; Päivi Ylä-Anttila; Tatyana Sandalova; Renhua Sun; Adnane Achour; Maria G. Masucci

doi:10.1371/journal.ppat.1008146

Loading metrics

Open Access

Peer-reviewed

Research Article

14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases

Soham Gupta ,

Contributed equally to this work with: Soham Gupta, Päivi Ylä-Anttila, Tatyana Sandalova

Roles Data curation, Formal analysis, Investigation, Writing – original draft

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0003-1136-3010

⨯
Päivi Ylä-Anttila ,

Contributed equally to this work with: Soham Gupta, Päivi Ylä-Anttila, Tatyana Sandalova

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0002-5794-5094

⨯
Tatyana Sandalova ,

Contributed equally to this work with: Soham Gupta, Päivi Ylä-Anttila, Tatyana Sandalova

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliations Science for Life Laboratory, Campus Solna, Stockholm, Sweden, Department of Medicine, Karolinska Institute, Stockholm, Sweden, Division of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯
Renhua Sun,

Roles Investigation

Affiliations Science for Life Laboratory, Campus Solna, Stockholm, Sweden, Department of Medicine, Karolinska Institute, Stockholm, Sweden, Division of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden

http://orcid.org/0000-0002-8203-4946

⨯
Adnane Achour,

Roles Supervision, Writing – review & editing

Affiliations Science for Life Laboratory, Campus Solna, Stockholm, Sweden, Department of Medicine, Karolinska Institute, Stockholm, Sweden, Division of Infectious Diseases, Karolinska University Hospital, Stockholm, Sweden
⨯
Maria G. Masucci

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: maria.masucci@ki.se

Affiliation Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

http://orcid.org/0000-0002-5541-2809

⨯

14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases

Soham Gupta,
Päivi Ylä-Anttila,
Tatyana Sandalova,
Renhua Sun,
Adnane Achour,
Maria G. Masucci

Published: November 11, 2019
https://doi.org/10.1371/journal.ppat.1008146

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Ligases
Is the Subject Area "Ligases" applicable to this article?

Thanks for your feedback.
HeLa cells
Is the Subject Area "HeLa cells" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Ubiquitination
Is the Subject Area "Ubiquitination" applicable to this article?

Thanks for your feedback.
Dimers
Is the Subject Area "Dimers" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.