An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

• Rachel B. Currier ,

  Contributed equally to this work with: Rachel B. Currier, Kathrin Ulrich, Alejandro E. Leroux

  Roles Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Meridian Bioscience, Edge Business Centre, London, United Kingdom

  Affiliation Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany

  http://orcid.org/0000-0002-0381-3029

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• Kathrin Ulrich ,

  Contributed equally to this work with: Rachel B. Currier, Kathrin Ulrich, Alejandro E. Leroux

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany, Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

  http://orcid.org/0000-0001-7607-3060

  ⨯
• Alejandro E. Leroux ,

  Contributed equally to this work with: Rachel B. Currier, Kathrin Ulrich, Alejandro E. Leroux

  Roles Conceptualization, Funding acquisition, Investigation, Writing – review & editing

  Current address: Instituto de Investigación en Biomedicina de Buenos Aires (IBioBA)—CONICET—Polo Científico Tecnológico, Buenos Aires, Argentina

  Affiliation Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany

  http://orcid.org/0000-0001-6149-3572

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• Natalie Dirdjaja,

  Roles Investigation

  Affiliation Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany

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• Matías Deambrosi,

  Roles Investigation

  Affiliation Group Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay

  http://orcid.org/0000-0001-9111-5898

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• Mariana Bonilla,

  Roles Investigation, Writing – review & editing

  Affiliations Group Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay, Laboratorio de Fisicoquímica Biológica, Instituto de Química Biológica, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay

  http://orcid.org/0000-0002-9206-345X

  ⨯
• Yasar Luqman Ahmed,

  Roles Investigation

  Affiliation Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany

  http://orcid.org/0000-0002-4364-1372

  ⨯
• Lorenz Adrian,

  Roles Formal analysis, Investigation, Resources

  Affiliations Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental Research–UFZ, Leipzig, Germany, Fachgebiet Geobiotechnologie, Technische Universität Berlin, Berlin, Germany

  http://orcid.org/0000-0001-8205-0842

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• Haike Antelmann,

  Roles Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliation Institut für Biologie-Mikrobiologie, Freie Universität Berlin, Berlin, Germany

  http://orcid.org/0000-0002-1766-4386

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• Ursula Jakob,

  Roles Resources, Writing – review & editing

  Affiliation Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Marcelo A. Comini,

  Roles Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Group Redox Biology of Trypanosomes, Institut Pasteur de Montevideo, Montevideo, Uruguay

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• R. Luise Krauth-Siegel

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: luise.krauth-siegel@bzh.uni-heidelberg.de

  Affiliation Biochemie-Zentrum der Universität Heidelberg (BZH), Heidelberg, Germany

  http://orcid.org/0000-0003-2164-8116

  ⨯