In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis

• Frank Schmidt,

  Roles Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: Proteomics Core, Weill Cornell Medicine-Qatar, Qatar Foundation—Education City, Doha, Qatar

  Affiliation ZIK-FunGene, Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine Greifswald, Greifswald, Germany

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• Niamatullah Kakar ,

  Contributed equally to this work with: Niamatullah Kakar, Tanja C. Meyer

  Roles Investigation, Methodology

  Affiliation Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany

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• Tanja C. Meyer ,

  Contributed equally to this work with: Niamatullah Kakar, Tanja C. Meyer

  Roles Data curation, Investigation, Visualization

  Affiliation Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine of Greifswald, Greifswald, Germany

  http://orcid.org/0000-0002-4631-0528

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• Maren Depke,

  Roles Data curation, Investigation

  Affiliation Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine of Greifswald, Greifswald, Germany

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• Ilias Masouris,

  Roles Investigation

  Affiliation Clinic Grosshadern of the Ludwig-Maximilians University of Munich, Department of Neurology, Munich, Germany

  http://orcid.org/0000-0002-6926-0527

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• Gerhard Burchhardt,

  Roles Investigation, Supervision

  Affiliation Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany

  http://orcid.org/0000-0002-4664-2880

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• Alejandro Gómez-Mejia,

  Roles Investigation

  Affiliation Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany

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• Vishnu Dhople,

  Roles Investigation, Methodology

  Affiliation Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine of Greifswald, Greifswald, Germany

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• Leiv S. Håvarstein,

  Roles Writing – review & editing

  Affiliation Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway

  http://orcid.org/0000-0001-8250-4322

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• Zhi Sun,

  Roles Data curation

  Affiliation Institute for Systems Biology, Seattle, WA, United States of America

  http://orcid.org/0000-0003-3324-6851

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• Robert L. Moritz,

  Roles Data curation

  Affiliation Institute for Systems Biology, Seattle, WA, United States of America

  http://orcid.org/0000-0002-3216-9447

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• Uwe Völker,

  Roles Resources, Supervision, Validation

  Affiliations ZIK-FunGene, Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine Greifswald, Greifswald, Germany, Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University Medicine of Greifswald, Greifswald, Germany

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• Uwe Koedel ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Visualization, Writing – review & editing

  * E-mail: uwe.koedel@med.uni-muenchen.de (UK); sven.hammerschmidt@uni-greifswald.de (SH)

  Affiliation Clinic Grosshadern of the Ludwig-Maximilians University of Munich, Department of Neurology, Munich, Germany

  http://orcid.org/0000-0002-2666-0731

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• Sven Hammerschmidt

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: uwe.koedel@med.uni-muenchen.de (UK); sven.hammerschmidt@uni-greifswald.de (SH)

  Affiliation Department of Molecular Genetics and Infection Biology, Interfaculty Institute for Genetics and Functional Genomics, Center for Functional Genomics of Microbes, University of Greifswald, Greifswald, Germany

  http://orcid.org/0000-0002-6382-6681

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