Novel lactate dehydrogenase inhibitors with in vivo efficacy against Cryptosporidium parvum

Kun Li; Sara M. Nader; Xuejin Zhang; Benjamin C. Ray; Chi Yong Kim; Aditi Das; William H. Witola

doi:10.1371/journal.ppat.1007953

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Open Access

Peer-reviewed

Research Article

Novel lactate dehydrogenase inhibitors with in vivo efficacy against Cryptosporidium parvum

Kun Li,

Roles Formal analysis, Investigation, Validation

Current address: Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Sara M. Nader,

Roles Investigation

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

http://orcid.org/0000-0002-8406-441X

⨯
Xuejin Zhang,

Roles Investigation

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Benjamin C. Ray,

Roles Methodology

Affiliation Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

http://orcid.org/0000-0001-6678-6972

⨯
Chi Yong Kim,

Roles Investigation

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

http://orcid.org/0000-0003-4431-7504

⨯
Aditi Das,

Roles Methodology

Affiliation Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
William H. Witola

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: whwit35@illinois.edu

Affiliation Department of Pathobiology, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America

http://orcid.org/0000-0002-2308-0539

⨯

Novel lactate dehydrogenase inhibitors with in vivo efficacy against Cryptosporidium parvum

Kun Li,
Sara M. Nader,
Xuejin Zhang,
Benjamin C. Ray,
Chi Yong Kim,
Aditi Das,
William H. Witola

Published: July 29, 2019
https://doi.org/10.1371/journal.ppat.1007953

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Cryptosporidium parvum
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Recombinant proteins
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Parasitic diseases
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