Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation

• Chunling Wang ,

  Contributed equally to this work with: Chunling Wang, Henry Puerta-Guardo, Scott B. Biering

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  ⨯
• Henry Puerta-Guardo ,

  Contributed equally to this work with: Chunling Wang, Henry Puerta-Guardo, Scott B. Biering

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0003-3050-4480

  ⨯
• Scott B. Biering ,

  Contributed equally to this work with: Chunling Wang, Henry Puerta-Guardo, Scott B. Biering

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0003-1991-629X

  ⨯
• Dustin R. Glasner,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  ⨯
• Edwina B. Tran,

  Roles Investigation

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0002-7225-2261

  ⨯
• Mark Patana,

  Roles Investigation

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0001-8523-1104

  ⨯
• Trent A. Gomberg,

  Roles Investigation

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  ⨯
• Carmel Malvar,

  Roles Investigation

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  ⨯
• Nicholas T. N. Lo,

  Roles Investigation, Methodology

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0002-4289-1222

  ⨯
• Diego A. Espinosa,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0002-4364-5031

  ⨯
• Eva Harris

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: eharris@berkeley.edu

  Affiliation Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America

  http://orcid.org/0000-0002-7238-4037

  ⨯