Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment

• Frédéric D. Chevalier ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: fcheval@txbiomed.org (FDC); tanderso@txbiomed.org (TJCA)

  Affiliation Texas Biomedical Research Institute, San Antonio, Texas, United States of America

  http://orcid.org/0000-0003-2611-8106

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• Winka Le Clec’h,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Texas Biomedical Research Institute, San Antonio, Texas, United States of America

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• Marina McDew-White,

  Roles Investigation, Writing – review & editing

  Affiliation Texas Biomedical Research Institute, San Antonio, Texas, United States of America

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• Vinay Menon,

  Roles Investigation, Writing – review & editing

  Affiliation Texas Biomedical Research Institute, San Antonio, Texas, United States of America

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• Meghan A. Guzman,

  Roles Investigation, Writing – review & editing

  Affiliation Departments of Pathology and University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Stephen P. Holloway,

  Roles Investigation, Writing – review & editing

  Affiliation Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Xiaohang Cao,

  Roles Investigation, Writing – review & editing

  Affiliation Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Alexander B. Taylor,

  Roles Investigation, Project administration, Supervision, Writing – review & editing

  Affiliations Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, X-ray Crystallography Core Laboratory, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

  http://orcid.org/0000-0003-3517-6033

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• Safari Kinung'hi,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation National Institute for Medical Research, Mwanza, United Republic of Tanzania

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• Anouk N. Gouvras,

  Roles Investigation, Resources, Writing – review & editing

  Affiliations London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom, Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom

  http://orcid.org/0000-0002-7857-4309

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• Bonnie L. Webster,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliations London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom, Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom

  http://orcid.org/0000-0003-0930-9314

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• Joanne P. Webster,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliations London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom, Centre for Emerging, Endemic and Exotic Diseases (CEEED), Royal Veterinary College, University of London, United Kingdom

  http://orcid.org/0000-0001-8616-4919

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• Aidan M. Emery,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliations London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom, Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom

  http://orcid.org/0000-0001-9028-8586

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• David Rollinson,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliations London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom, Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom

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• Amadou Garba Djirmay,

  Roles Investigation, Writing – review & editing

  Affiliations Réseau International Schistosomiases Environnemental Aménagement et Lutte (RISEAL), Niamey, Niger, World Health Organization, Geneva, Switzerland

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• Khalid M. Al Mashikhi,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman

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• Salem Al Yafae,

  Roles Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman

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• Mohamed A. Idris,

  Roles Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Sultan Qaboos University, Muscat, Sultanate of Oman

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• Hélène Moné,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Host-Pathogen-Environment Interactions laboratory, University of Perpignan, Perpignan, France

  http://orcid.org/0000-0003-3180-344X

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• Gabriel Mouahid,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Host-Pathogen-Environment Interactions laboratory, University of Perpignan, Perpignan, France

  http://orcid.org/0000-0003-0332-5081

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• P. John Hart,

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliations Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America, X-ray Crystallography Core Laboratory, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Philip T. LoVerde,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Departments of Pathology and University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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•  [ ... ],
• Timothy J. C. Anderson

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: fcheval@txbiomed.org (FDC); tanderso@txbiomed.org (TJCA)

  Affiliation Texas Biomedical Research Institute, San Antonio, Texas, United States of America

  http://orcid.org/0000-0002-0191-0204

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