The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming

• Aline Sardinha-Silva,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

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• Flávia C. Mendonça-Natividade,

  Roles Methodology

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

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• Camila F. Pinzan,

  Roles Methodology

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

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• Carla D. Lopes,

  Roles Methodology

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

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• Diego L. Costa,

  Roles Formal analysis, Methodology, Visualization

  Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

  http://orcid.org/0000-0002-9440-2814

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• Damien Jacot,

  Roles Methodology, Resources

  Affiliation Department of Microbiology and Molecular Medicine, CMU, University of Geneva, Switzerland

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• Fabricio F. Fernandes,

  Roles Methodology

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

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• André L. V. Zorzetto-Fernandes,

  Roles Methodology

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

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• Nicholas J. Gay,

  Roles Resources

  Affiliation Department of Biochemistry, Cambridge University, United Kingdom

  http://orcid.org/0000-0002-2782-7169

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• Alan Sher,

  Roles Resources, Writing – review & editing

  Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

  http://orcid.org/0000-0001-7053-2895

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• Dragana Jankovic,

  Roles Resources, Writing – review & editing

  Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

  http://orcid.org/0000-0001-7360-1809

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• Dominique Soldati-Favre,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Department of Microbiology and Molecular Medicine, CMU, University of Geneva, Switzerland

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• Michael E. Grigg ,

  Roles Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: griggm@niaid.nih.gov (MEG); mcrbarre@fmrp.usp.br (MCRB)

  Affiliation Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

  http://orcid.org/0000-0003-3465-3782

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• Maria Cristina Roque-Barreira

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: griggm@niaid.nih.gov (MEG); mcrbarre@fmrp.usp.br (MCRB)

  Affiliation Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirao Preto Medical School, University of Sao Paulo- USP (FMRP/USP), Ribeirao Preto, Sao Paulo, Brazil

  http://orcid.org/0000-0001-7425-0908

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