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Open Access
Peer-reviewed
Research Article
The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
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Liwen Deng,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Biology, San Diego State University, San Diego, CA, United States of America, Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States of America
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Brady L. Spencer,
Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing
Affiliation Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States of America
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Joshua A. Holmes,
Roles Formal analysis, Investigation, Methodology, Validation
Affiliation Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States of America
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Rong Mu,
Roles Investigation
Affiliation Department of Biology, San Diego State University, San Diego, CA, United States of America
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Sara Rego,
Roles Investigation
Affiliation Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, United Kingdom
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Thomas A. Weston,
Roles Investigation
Affiliation Department of Biology, San Diego State University, San Diego, CA, United States of America
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Yoonsung Hu,
Roles Investigation
Affiliation Department of Biological Sciences, Mississippi State University, Mississippi State, MS, United States of America
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Glenda F. Sanches,
Roles Investigation
Affiliations Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States of America, Laboratory of Molecular Biology and Physiology of Streptococci, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rio de Janeiro, Brazil
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Sunghyun Yoon,
Roles Investigation
Affiliation Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, United States of America
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Nogi Park,
Roles Investigation
Affiliation Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, United States of America
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Prescilla E. Nagao,
Roles Resources
Affiliation Laboratory of Molecular Biology and Physiology of Streptococci, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rio de Janeiro, Brazil
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Howard F. Jenkinson,
Roles Conceptualization, Resources, Supervision
Affiliation Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, United Kingdom
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Justin A. Thornton,
Roles Conceptualization, Investigation, Supervision
Affiliation Department of Biological Sciences, Mississippi State University, Mississippi State, MS, United States of America
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Keun Seok Seo,
Roles Conceptualization, Investigation, Methodology, Supervision
Affiliation Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS, United States of America
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Angela H. Nobbs,
Roles Conceptualization, Resources, Supervision, Writing – review & editing
Affiliation Bristol Dental School, University of Bristol, Lower Maudlin Street, Bristol, United Kingdom
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Kelly S. Doran
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: kelly.doran@ucdenver.edu
Affiliations Department of Biology, San Diego State University, San Diego, CA, United States of America, Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, United States of America
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The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis
- Liwen Deng,
- Brady L. Spencer,
- Joshua A. Holmes,
- Rong Mu,
- Sara Rego,
- Thomas A. Weston,
- Yoonsung Hu,
- Glenda F. Sanches,
- Sunghyun Yoon,
- Nogi Park
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- Published: June 10, 2019
- https://doi.org/10.1371/journal.ppat.1007848