Viral engagement with host receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid

• Liang Sun,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  ⨯
• Hyunwook Lee,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – original draft

  Affiliation Department of Biochemistry and Molecular Biology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  http://orcid.org/0000-0002-5428-8594

  ⨯
• Hendrik Jan Thibaut,

  Roles Formal analysis, Writing – review & editing

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0001-5785-8276

  ⨯
• Kristina Lanko,

  Roles Investigation, Methodology

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0002-0749-0079

  ⨯
• Eva Rivero-Buceta,

  Roles Resources

  Affiliation Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (IQM, CSIC), Madrid, Spain

  ⨯
• Carol Bator,

  Roles Investigation, Methodology

  Affiliation Department of Biochemistry and Molecular Biology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Belen Martinez-Gualda,

  Roles Resources

  Affiliation Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (IQM, CSIC), Madrid, Spain

  ⨯
• Kai Dallmeier,

  Roles Methodology, Resources

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0002-8117-9166

  ⨯
• Leen Delang,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0002-8874-675X

  ⨯
• Pieter Leyssen,

  Roles Conceptualization, Project administration, Supervision

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0002-7537-1688

  ⨯
• Federico Gago,

  Roles Data curation, Formal analysis, Writing – original draft

  Affiliation Department of Biomedical Sciences, School of Medicine and Health Sciences, University of Alcalá, Unidad Asociada IQM-CSIC, Madrid, Spain

  http://orcid.org/0000-0002-3071-4878

  ⨯
• Ana San-Félix,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Instituto de Química Médica, Consejo Superior de Investigaciones Científicas (IQM, CSIC), Madrid, Spain

  http://orcid.org/0000-0003-4271-7598

  ⨯
• Susan Hafenstein ,

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: shafenstein@pennstatehealth.psu.edu (SH); johan.neyts@kuleuven.be (JN)

  Affiliations Department of Biochemistry and Molecular Biology, Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Department of Medicine, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America

  http://orcid.org/0000-0003-2609-4036

  ⨯
• Carmen Mirabelli,

  Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  ⨯
• Johan Neyts

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: shafenstein@pennstatehealth.psu.edu (SH); johan.neyts@kuleuven.be (JN)

  Affiliation KU Leuven–University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium

  http://orcid.org/0000-0002-0033-7514

  ⨯