Early existence and biochemical evolution characterise acutely synaptotoxic PrP^Sc

• Simote Totauhelotu Foliaki,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia

  http://orcid.org/0000-0001-7450-6926

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• Victoria Lewis,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia, Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia

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• Abu Mohammed Taufiqual Islam,

  Roles Resources

  Affiliation Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia

  http://orcid.org/0000-0002-9716-6351

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• Laura Jane Ellett,

  Roles Resources

  Affiliations Department of Pathology The University of Melbourne, Parkville, Victoria, Australia, Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

  http://orcid.org/0000-0002-3973-0970

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• Matteo Senesi,

  Roles Resources

  Affiliation Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia

  http://orcid.org/0000-0002-3968-2075

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• David Isaac Finkelstein,

  Roles Supervision

  Affiliation Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia

  http://orcid.org/0000-0002-8167-4917

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• Blaine Roberts,

  Roles Methodology, Supervision

  Affiliation Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia

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• Victoria A. Lawson,

  Roles Resources, Writing – review & editing

  Affiliations Department of Pathology The University of Melbourne, Parkville, Victoria, Australia, Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia

  http://orcid.org/0000-0002-7362-7176

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• Paul Anthony Adlard,

  Roles Supervision, Writing – review & editing

  Affiliation Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia

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• Steven John Collins

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: stevenjc@unimelb.edu.au

  Affiliations Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, Victoria, Australia, Florey Institute of Neuroscience and Mental Health, Parkville, Victoria, Australia

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