SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Ruikang Liu; Jorge D. Mendez-Rios; Chen Peng; Wei Xiao; Andrea S. Weisberg; Linda S. Wyatt; Bernard Moss

doi:10.1371/journal.ppat.1007710

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Peer-reviewed

Research Article

SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Ruikang Liu,

Roles Investigation, Methodology, Validation, Writing – review & editing

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Jorge D. Mendez-Rios,

Roles Data curation, Investigation, Software, Writing – review & editing

Current address: Caja de Seguro Social, Genetics and Cytogenetics Section, Republic of Panama

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

http://orcid.org/0000-0001-8501-9672

⨯
Chen Peng,

Roles Investigation

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Wei Xiao,

Roles Investigation

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Andrea S. Weisberg,

Roles Investigation, Visualization

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Linda S. Wyatt,

Roles Investigation, Supervision

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Bernard Moss

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

* E-mail: bmoss@nih.gov

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

http://orcid.org/0000-0002-2154-8564

⨯

SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Ruikang Liu,
Jorge D. Mendez-Rios,
Chen Peng,
Wei Xiao,
Andrea S. Weisberg,
Linda S. Wyatt,
Bernard Moss

Published: May 30, 2019
https://doi.org/10.1371/journal.ppat.1007710

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