Unmasking cellular response of a bloom-forming alga to viral infection by resolving expression profiles at a single-cell level

Shilo Rosenwasser; Uri Sheyn; Miguel J. Frada; David Pilzer; Ron Rotkopf; Assaf Vardi

doi:10.1371/journal.ppat.1007708

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Open Access

Peer-reviewed

Research Article

Unmasking cellular response of a bloom-forming alga to viral infection by resolving expression profiles at a single-cell level

Shilo Rosenwasser ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: shilo.rosenwaser@mail.huji.ac.il (SR); assaf.vardi@weizmann.ac.il (AV)

Affiliations Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel, The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture, The Hebrew University, Rehovot, Israel
⨯
Uri Sheyn,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel
⨯
Miguel J. Frada,

Roles Formal analysis, Investigation, Methodology

Affiliations Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel, The Interuniversity Institute for Marine Sciences, Eilat, Israel, Department of Ecology, Evolution and Behavior, Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
⨯
David Pilzer,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Genomic Technologies Unit, Weizmann Institute of Science, Rehovot, Israel
⨯
Ron Rotkopf,

Roles Data curation, Formal analysis, Methodology, Software

Affiliation Bioinformatics and Biological Computing Unit, Weizmann Institute of Science, Rehovot, Israel

http://orcid.org/0000-0001-9503-7348

⨯
Assaf Vardi

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: shilo.rosenwaser@mail.huji.ac.il (SR); assaf.vardi@weizmann.ac.il (AV)

Affiliation Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel

http://orcid.org/0000-0002-7079-0234

⨯

Unmasking cellular response of a bloom-forming alga to viral infection by resolving expression profiles at a single-cell level

Shilo Rosenwasser,
Uri Sheyn,
Miguel J. Frada,
David Pilzer,
Ron Rotkopf,
Assaf Vardi

Published: April 24, 2019
https://doi.org/10.1371/journal.ppat.1007708

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Virus effects on host gene expression
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Viral transmission and infection
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Cell metabolism
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Gene expression
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Viral genes
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Viral gene expression
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Host-pathogen interactions
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Sphingolipids
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