Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

• Aurélie Crabbé ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft

  * E-mail: aurelie.crabbe@ugent.be

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0003-3084-4418

  ⨯
• Lisa Ostyn,

  Roles Methodology

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  ⨯
• Sorien Staelens,

  Roles Methodology

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  ⨯
• Charlotte Rigauts,

  Roles Methodology

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  ⨯
• Martijn Risseeuw,

  Roles Methodology

  Affiliation Laboratory for Medicinal Chemistry, Ghent University, Ghent, Belgium

  ⨯
• Maarten Dhaenens,

  Roles Investigation, Methodology

  Affiliation ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0002-9801-3509

  ⨯
• Simon Daled,

  Roles Methodology

  Affiliation ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0001-8129-2217

  ⨯
• Heleen Van Acker,

  Roles Investigation

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0002-7145-9826

  ⨯
• Dieter Deforce,

  Roles Methodology

  Affiliation ProGenTomics, Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium

  ⨯
• Serge Van Calenbergh,

  Roles Methodology, Resources

  Affiliation Laboratory for Medicinal Chemistry, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0002-4201-1264

  ⨯
• Tom Coenye

  Roles Funding acquisition, Investigation, Writing – review & editing

  Affiliation Laboratory of Pharmaceutical Microbiology, Ghent University, Ghent, Belgium

  http://orcid.org/0000-0002-6407-0601

  ⨯