RNAi-based small molecule repositioning reveals clinically approved urea-based kinase inhibitors as broadly active antivirals

• Markus Lesch,

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany

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• Madlen Luckner,

  Roles Investigation

  Affiliation Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany

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• Michael Meyer,

  Roles Formal analysis, Writing – review & editing

  Affiliation Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany

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• Friderike Weege,

  Roles Investigation

  Affiliation Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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• Isabella Gravenstein,

  Roles Investigation

  Affiliation Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany

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• Martin Raftery,

  Roles Investigation, Resources

  Affiliation Institute of Virology, Charité University Medicine, Berlin, Germany

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• Christian Sieben,

  Roles Investigation, Resources

  Affiliation Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany

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• Laura Martin-Sancho,

  Roles Investigation

  Affiliation Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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• Aki Imai-Matsushima,

  Roles Investigation, Methodology

  Affiliation Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany

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• Robert-William Welke,

  Roles Investigation, Resources

  Affiliation Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany

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• Rebecca Frise,

  Roles Investigation

  Affiliation Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom

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• Wendy Barclay,

  Roles Investigation, Resources

  Affiliation Section of Virology, Department of Medicine, Imperial College London, St Mary's Campus, London, United Kingdom

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• Günther Schönrich,

  Roles Investigation, Resources

  Affiliation Institute of Virology, Charité University Medicine, Berlin, Germany

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• Andreas Herrmann,

  Roles Investigation, Resources

  Affiliation Group of Molecular Biophysics, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany

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• Thomas F. Meyer ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: meyer@mpiib-berlin.mpg.de (TFM); karlas@mpiib-berlin.mpg.de (AK)

  Affiliations Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany

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•  [ ... ],
• Alexander Karlas

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: meyer@mpiib-berlin.mpg.de (TFM); karlas@mpiib-berlin.mpg.de (AK)

  Current address: Viral Vaccines Development, ProBioGen AG, Berlin, Germany

  Affiliations Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany, Steinbeis Innovation Center for Systems Biomedicine, Falkensee, Germany

  http://orcid.org/0000-0002-2187-2057

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