Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants

• Derek W. Trobaugh,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Center for Vaccine Research, Department of Immunology, University of Pittsburgh, Pittsburgh, PA United States of America

  http://orcid.org/0000-0002-7312-0260

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• Chengqun Sun,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Center for Vaccine Research, Department of Immunology, University of Pittsburgh, Pittsburgh, PA United States of America

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• Matthew D. Dunn,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Center for Vaccine Research, Department of Immunology, University of Pittsburgh, Pittsburgh, PA United States of America

  http://orcid.org/0000-0003-0378-5838

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• Douglas S. Reed,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Center for Vaccine Research, Department of Immunology, University of Pittsburgh, Pittsburgh, PA United States of America

  http://orcid.org/0000-0003-0076-9023

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• William B. Klimstra

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Klimstra@pitt.edu

  Affiliation Center for Vaccine Research, Department of Immunology, University of Pittsburgh, Pittsburgh, PA United States of America

  http://orcid.org/0000-0003-4506-7842

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