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Open Access
Peer-reviewed
Research Article
EBNA3C facilitates RASSF1A downregulation through ubiquitin-mediated degradation and promoter hypermethylation to drive B-cell proliferation
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Shengwei Zhang,
Roles Conceptualization, Formal analysis, Investigation, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Yonggang Pei,
Roles Conceptualization, Methodology, Resources, Validation
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Fengchao Lang,
Roles Methodology, Resources, Validation
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Kunfeng Sun,
Roles Methodology, Resources
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Rajnish Kumar Singh,
Roles Methodology, Resources, Validation
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Zachary L. Lamplugh,
Roles Methodology, Resources
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Abhik Saha,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Life Sciences, Presidency University, Kolkata, India
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Erle S. Robertson
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: erle@pennmedicine.upenn.edu
Affiliation Department of Otorhinolaryngology-Head and Neck Surgery, and Microbiology, the Tumor Virology Program, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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EBNA3C facilitates RASSF1A downregulation through ubiquitin-mediated degradation and promoter hypermethylation to drive B-cell proliferation
- Shengwei Zhang,
- Yonggang Pei,
- Fengchao Lang,
- Kunfeng Sun,
- Rajnish Kumar Singh,
- Zachary L. Lamplugh,
- Abhik Saha,
- Erle S. Robertson
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- Published: January 7, 2019
- https://doi.org/10.1371/journal.ppat.1007514