Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection

• Reece J. Knippel,

  Roles Conceptualization, Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America, Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN, United States of America

  http://orcid.org/0000-0002-3129-5468

  ⨯
• Joseph P. Zackular,

  Roles Investigation, Writing – review & editing

  Affiliations Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America, Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN, United States of America

  http://orcid.org/0000-0002-3228-3055

  ⨯
• Jessica L. Moore,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Biochemistry, Vanderbilt University, Nashville, TN, United States of America

  ⨯
• Arianna I. Celis,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, United States of America

  ⨯
• Andy Weiss,

  Roles Formal analysis, Visualization, Writing – review & editing

  Affiliations Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America, Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN, United States of America

  ⨯
• M. Kay Washington,

  Roles Formal analysis

  Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America

  ⨯
• Jennifer L. DuBois,

  Roles Resources, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, United States of America

  ⨯
• Richard M. Caprioli,

  Roles Resources, Writing – review & editing

  Affiliation Department of Chemistry, Vanderbilt University, Nashville, TN, United States of America

  ⨯
• Eric P. Skaar

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: eric.skaar@vumc.org

  Affiliations Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States of America, Vanderbilt Institute for Infection, Immunology and Inflammation, Vanderbilt University Medical Center, Nashville, TN, United States of America

  http://orcid.org/0000-0001-5094-8105

  ⨯