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Open Access
Peer-reviewed
Research Article
EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma
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Xiaoming Lyu ,
Contributed equally to this work with: Xiaoming Lyu, Jianguo Wang, Xia Guo
Roles Conceptualization, Funding acquisition, Project administration, Resources, Validation, Writing – review & editing
* E-mail: lvxiaoming6108@126.com (XL); q_chiang1020@163.com (QJ); xinli268@gmail.com (XL)
¶‡ These authors are joint senior authors on this work.
Affiliation Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, P.R. China
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Jianguo Wang ,
Contributed equally to this work with: Xiaoming Lyu, Jianguo Wang, Xia Guo
Roles Investigation, Methodology
Affiliation Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, P.R. China
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Xia Guo ,
Contributed equally to this work with: Xiaoming Lyu, Jianguo Wang, Xia Guo
Roles Resources
Affiliation Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China
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Gongfa Wu,
Roles Investigation, Methodology
Affiliation Department of Pathology, Zengcheng District People’s Hospital of Guangzhou City, Guangzhou, P.R. China
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Yang Jiao,
Roles Investigation
Affiliation Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China
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Oluwasijibomi Damola Faleti,
Roles Investigation
Affiliation Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China
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Pengfei Liu,
Roles Investigation, Methodology
Affiliation Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, P.R. China
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Tielian Liu,
Roles Investigation, Methodology
Affiliation Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, P.R. China
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Yufei Long,
Roles Investigation, Methodology
Affiliation Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China
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Tuotuo Chong,
Roles Investigation, Methodology
Affiliation Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China
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Xu Yang,
Roles Investigation, Methodology
Affiliation Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China
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Jing Huang,
Roles Investigation, Methodology
Affiliation Department of laboratory medicine, The Third Affiliated Hospital, Southern Medical University, Guangzhou, P.R. China
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Mingliang He,
Roles Resources, Validation, Writing – review & editing
Affiliation Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China
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Chi Man Tsang,
Roles Resources
Affiliations School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China, Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong SAR, China
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Sai Wah Tsao,
Roles Resources
Affiliation School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China
⨯ - Qian Wang,
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Qiang Jiang ,
Roles Investigation, Methodology, Validation, Writing – original draft
* E-mail: lvxiaoming6108@126.com (XL); q_chiang1020@163.com (QJ); xinli268@gmail.com (XL)
¶‡ These authors are joint senior authors on this work.
Affiliations Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China, Department of Oncology, Henan Provincial People’s Hospital, Zhengzhou, P.R. China
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Xin Li
Roles Conceptualization, Funding acquisition, Resources, Validation, Writing – review & editing
* E-mail: lvxiaoming6108@126.com (XL); q_chiang1020@163.com (QJ); xinli268@gmail.com (XL)
¶‡ These authors are joint senior authors on this work.
Affiliation Shenzhen Key Laboratory of Viral Oncology, the Clinical Innovation & Research Center (CIRC), Shenzhen Hospital, Southern Medical University, Shenzhen, China
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EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma
- Xiaoming Lyu,
- Jianguo Wang,
- Xia Guo,
- Gongfa Wu,
- Yang Jiao,
- Oluwasijibomi Damola Faleti,
- Pengfei Liu,
- Tielian Liu,
- Yufei Long,
- Tuotuo Chong
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- Published: December 17, 2018
- https://doi.org/10.1371/journal.ppat.1007484