A dual regulatory circuit consisting of S-adenosylmethionine decarboxylase protein and its reaction product controls expression of the paralogous activator prozyme in Trypanosoma brucei

• Manish M. Patel,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Harry Hines Blvd, Dallas, TX, United States of America

  http://orcid.org/0000-0002-7041-0510

  ⨯
• Oleg A. Volkov,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Harry Hines Blvd, Dallas, TX, United States of America

  http://orcid.org/0000-0001-6487-9518

  ⨯
• Christopher Leija,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Harry Hines Blvd, Dallas, TX, United States of America

  http://orcid.org/0000-0002-0041-2502

  ⨯
• Andrew Lemoff,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Harry Hines Blvd, Dallas, TX, United States of America

  ⨯
• Margaret A. Phillips

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: margaret.phillips@UTSouthwestern.edu

  Affiliation Department of Biochemistry, University of Texas Southwestern Medical Center at Dallas, Harry Hines Blvd, Dallas, TX, United States of America

  http://orcid.org/0000-0001-5250-5578

  ⨯