A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

• Marco Bardelli ,

  Contributed equally to this work with: Marco Bardelli, Karl Frontzek

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  http://orcid.org/0000-0002-1501-9252

  ⨯
• Karl Frontzek ,

  Contributed equally to this work with: Marco Bardelli, Karl Frontzek

  Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-0945-8857

  ⨯
• Luca Simonelli,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  ⨯
• Simone Hornemann,

  Roles Data curation, Investigation

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-2674-9891

  ⨯
• Mattia Pedotti,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  ⨯
• Federica Mazzola,

  Roles Formal analysis

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  ⨯
• Manfredi Carta,

  Roles Formal analysis

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-0757-3616

  ⨯
• Valeria Eckhardt,

  Roles Data curation, Investigation

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0003-1564-5867

  ⨯
• Rocco D’Antuono,

  Roles Methodology

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  ⨯
• Tommaso Virgilio,

  Roles Methodology

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  http://orcid.org/0000-0002-9326-8828

  ⨯
• Santiago F. González,

  Roles Methodology

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  ⨯
• Adriano Aguzzi ,

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: adriano.aguzzi@usz.ch (AA); luca.varani@irb.usi.ch (LV)

  Affiliation Institute of Neuropathology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-0344-6708

  ⨯
• Luca Varani

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: adriano.aguzzi@usz.ch (AA); luca.varani@irb.usi.ch (LV)

  Affiliation Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland

  http://orcid.org/0000-0002-0963-0987

  ⨯