Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway

• Weijian Ye ,

  Contributed equally to this work with: Weijian Ye, Marvin Chew

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations School of Biological Sciences, Nanyang Technological University, Singapore, Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore

  http://orcid.org/0000-0002-3247-0686

  ⨯
• Marvin Chew ,

  Contributed equally to this work with: Weijian Ye, Marvin Chew

  Roles Investigation, Methodology

  Affiliations School of Biological Sciences, Nanyang Technological University, Singapore, Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore

  ⨯
• Jue Hou,

  Roles Methodology

  Affiliation Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore

  http://orcid.org/0000-0001-9913-8365

  ⨯
• Fritz Lai,

  Roles Methodology

  Affiliation Humanized Mouse Unit, Institute of Molecular and Cell Biology, Agency of Science, Technology and Research, Singapore

  ⨯
• Stije J. Leopold,

  Roles Resources

  Affiliations Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  http://orcid.org/0000-0002-0482-5689

  ⨯
• Hooi Linn Loo,

  Roles Investigation

  Affiliation Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore

  ⨯
• Aniruddha Ghose,

  Roles Resources

  Affiliation Department of Internal Medicine, Chittagong Medical College Hospital, Chittagong, Bangladesh

  ⨯
• Ashok K. Dutta,

  Roles Resources

  Affiliation Department of Internal Medicine, Chittagong Medical College Hospital, Chittagong, Bangladesh

  http://orcid.org/0000-0002-4505-2985

  ⨯
• Qingfeng Chen,

  Roles Methodology

  Affiliation Humanized Mouse Unit, Institute of Molecular and Cell Biology, Agency of Science, Technology and Research, Singapore

  ⨯
• Eng Eong Ooi,

  Roles Resources

  Affiliations Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore, Duke-National University of Singapore Medical School, Singapore

  http://orcid.org/0000-0002-0520-1544

  ⨯
• Nicholas J. White,

  Roles Resources

  Affiliations Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  http://orcid.org/0000-0002-1897-1978

  ⨯
• Arjen M. Dondorp,

  Roles Resources

  Affiliations Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  ⨯
• Peter Preiser ,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: PRPreiser@ntu.edu.sg (PP); jchen@mit.edu (JC)

  Affiliations School of Biological Sciences, Nanyang Technological University, Singapore, Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore

  http://orcid.org/0000-0003-4331-7000

  ⨯
• Jianzhu Chen

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  * E-mail: PRPreiser@ntu.edu.sg (PP); jchen@mit.edu (JC)

  Affiliations Singapore-MIT Alliance for Research and Technology, Infectious Disease Interdisciplinary Research Group, Singapore, Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, United States of America

  http://orcid.org/0000-0002-5687-6154

  ⨯