Type I IFNs drive hematopoietic stem and progenitor cell collapse via impaired proliferation and increased RIPK1-dependent cell death during shock-like ehrlichial infection

• Julianne N. P. Smith,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Current address: Case Western Reserve University, Department of Medicine, Cleveland, Ohio, United States of America

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

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• Yubin Zhang,

  Roles Data curation, Formal analysis

  Current address: School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, China

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

  ⨯
• Jing Jing Li,

  Roles Data curation, Formal analysis

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

  ⨯
• Amanda McCabe,

  Roles Data curation

  Current address: Children’s Hospital Boston, Division of Hematology/Oncology, Harvard Medical School, Karp Family Research Lab, Boston, Massachusetts, United States of America

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

  ⨯
• Hui Jin Jo,

  Roles Data curation, Formal analysis

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

  ⨯
• Jackson Maloney,

  Roles Data curation

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

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• Katherine C. MacNamara

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: MacnamK@amc.edu

  ¶‡ This author is the lead contact for this work.

  Affiliation Department of Immunology and Microbial Disease, Albany Medical College, Albany, New York, United States of America

  http://orcid.org/0000-0001-6202-4700

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