A VP1 mutation acquired during an enterovirus 71 disseminated infection confers heparan sulfate binding ability and modulates ex vivo tropism

• Eirini D. Tseligka,

  Roles Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

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• Komla Sobo,

  Roles Investigation, Methodology

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

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• Luc Stoppini,

  Roles Methodology, Resources

  Affiliation Tissue Engineering Laboratory, HES-SO/University of Applied Sciences, Geneva, Western Switzerland

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• Valeria Cagno,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

  http://orcid.org/0000-0002-5597-334X

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• Fabien Abdul,

  Roles Methodology, Supervision

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

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• Isabelle Piuz,

  Roles Methodology

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

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• Pascal Meylan,

  Roles Methodology, Resources, Writing – review & editing

  Affiliation Institute of Microbiology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland

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• Song Huang,

  Roles Resources

  Affiliation Epithelix Sàrl, Geneva, Switzerland

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• Samuel Constant,

  Roles Resources

  Affiliation Epithelix Sàrl, Geneva, Switzerland

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• Caroline Tapparel

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Caroline.Tapparel@unige.ch

  Affiliation Department of Microbiology and Molecular Medicine, University of Geneva Medical School, Geneva, Switzerland

  http://orcid.org/0000-0002-0411-6567

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