Chronic schistosomiasis suppresses HIV-specific responses to DNA-MVA and MVA-gp140 Env vaccine regimens despite antihelminthic treatment and increases helminth-associated pathology in a mouse model

• Godfrey A. Dzhivhuho,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Current address: Department of Microbiology, Immunology and Cancer Biology, Myles H. Thaler Center for AIDS and Human Retrovirus Research, University of Virginia, Charlottesville, Virginia, United States of America.

  Affiliation Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa

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• Samantha A. Rehrl,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa

  http://orcid.org/0000-0003-0005-8942

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• Hlumani Ndlovu,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Integrative Biomedical Sciences, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa

  http://orcid.org/0000-0003-0137-1439

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• William G. C. Horsnell,

  Roles Supervision, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom, Laboratory of Molecular and Experimental Immunology and Neurogenetics, Centre Nationnal de la Recherche Scientifique, University of Orleans and Le Studium Institute for Advanced Studies, Rue Dupanloup, Orléans, France

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• Frank Brombacher,

  Roles Resources, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, International Centre for Genomic Engineering and Biotechnology–Cape Town Component, Cape Town, Western Cape, South Africa, South African Medical Research Council, Cape Town, Western Cape, South Africa

  http://orcid.org/0000-0001-8881-6781

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• Anna-Lise Williamson,

  Roles Resources, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa

  http://orcid.org/0000-0002-5467-1200

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• Gerald K. Chege

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: Gerald.Chege@mrc.ac.za

  Affiliations Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, Western Cape, South Africa, South African Medical Research Council, Cape Town, Western Cape, South Africa

  http://orcid.org/0000-0003-3986-9638

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