De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions

• Yoann Millerioux,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliations Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France, Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France

  http://orcid.org/0000-0003-3782-3118

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• Muriel Mazet,

  Roles Investigation, Methodology

  Affiliations Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France, Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France

  http://orcid.org/0000-0001-8916-4551

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• Guillaume Bouyssou,

  Roles Investigation, Methodology

  Affiliation Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France

  ⨯
• Stefan Allmann,

  Roles Investigation, Methodology

  Affiliations Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France, Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France

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• Tiila-Riikka Kiema,

  Roles Investigation, Methodology, Supervision

  Affiliation Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland

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• Eloïse Bertiaux,

  Roles Investigation, Methodology

  Affiliation Trypanosome Transmission Group, Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, INSERM U1201, Institut Pasteur, Paris, France

  http://orcid.org/0000-0001-6593-083X

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• Laetitia Fouillen,

  Roles Investigation, Methodology

  Affiliations Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France, Metabolome Facility of Bordeaux, Functional Genomics Center, Villenave d'Ornon

  http://orcid.org/0000-0002-1204-9296

  ⨯
• Chandan Thapa,

  Roles Investigation, Methodology

  Current address: University of Jyväskylä, Jyväskylä, Finland

  Affiliation Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland

  http://orcid.org/0000-0002-9554-518X

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• Marc Biran,

  Roles Investigation, Methodology

  Affiliation Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France

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• Nicolas Plazolles,

  Roles Investigation, Methodology

  Affiliation Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France

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• Franziska Dittrich-Domergue,

  Roles Methodology

  Affiliation Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France

  ⨯
• Aline Crouzols,

  Roles Investigation, Methodology

  Affiliation Trypanosome Transmission Group, Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, INSERM U1201, Institut Pasteur, Paris, France

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• Rik K. Wierenga,

  Roles Conceptualization, Supervision

  Affiliation Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland

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• Brice Rotureau,

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  Affiliation Trypanosome Transmission Group, Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, INSERM U1201, Institut Pasteur, Paris, France

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• Patrick Moreau,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France

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•  [ ... ],
• Frédéric Bringaud

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

  * E-mail: frederic.bringaud@u-bordeaux.fr

  Affiliations Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France, Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France

  http://orcid.org/0000-0003-4552-6877

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