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Open Access
Peer-reviewed
Research Article
HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition
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Nicolas Jouand,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft
Affiliations Centre de Recherche en Transplantation et Immunologie (CRTI), UMR1064, INSERM, Université de Nantes, Nantes, France, Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France, CRCINA, UMR1232, INSERM, Université d’Angers, Université de Nantes, Nantes, France, LabEx Immunology-Graft-Oncology (IGO), Nantes, France
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Céline Bressollette-Bodin,
Roles Conceptualization, Formal analysis, Investigation, Resources
Affiliations Centre de Recherche en Transplantation et Immunologie (CRTI), UMR1064, INSERM, Université de Nantes, Nantes, France, Laboratoire de Virologie, CHU Nantes, Nantes, France
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Nathalie Gérard,
Roles Data curation, Investigation, Methodology
Affiliations Centre de Recherche en Transplantation et Immunologie (CRTI), UMR1064, INSERM, Université de Nantes, Nantes, France, Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France
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Magali Giral,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources
Affiliations Centre de Recherche en Transplantation et Immunologie (CRTI), UMR1064, INSERM, Université de Nantes, Nantes, France, Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France
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Pierrick Guérif,
Roles Resources
Affiliation Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France
⨯ - Audrey Rodallec,
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Romain Oger,
Roles Methodology
Affiliation CRCINA, UMR1232, INSERM, Université d’Angers, Université de Nantes, Nantes, France
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Tiphaine Parrot,
Roles Investigation, Methodology
Current address: Karolinska Institute, Department of Medicine, Stockholm, Sweden
Affiliation CRCINA, UMR1232, INSERM, Université d’Angers, Université de Nantes, Nantes, France
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Mathilde Allard,
Roles Conceptualization, Investigation, Methodology
Current address: Laboratoire d'Immunologie des Tumeurs, Faculté de Médecine, Université de Geneve / Hôpitaux Universitaires de Geneve, Geneve, Switzerland
Affiliation CRCINA, UMR1232, INSERM, Université d’Angers, Université de Nantes, Nantes, France
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Anne Cesbron-Gautier,
Roles Resources
Affiliation Etablissement Français du Sang (EFS), Région des Pays de la Loire, Nantes, France
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Nadine Gervois ,
Contributed equally to this work with: Nadine Gervois, Béatrice Charreau
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft
* E-mail: Nadine.Gervois@univ-nantes.fr (NG); Beatrice.Charreau@univ-nantes.fr (BC)
Affiliations CRCINA, UMR1232, INSERM, Université d’Angers, Université de Nantes, Nantes, France, LabEx Immunology-Graft-Oncology (IGO), Nantes, France
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Béatrice Charreau
Contributed equally to this work with: Nadine Gervois, Béatrice Charreau
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft
* E-mail: Nadine.Gervois@univ-nantes.fr (NG); Beatrice.Charreau@univ-nantes.fr (BC)
Affiliations Centre de Recherche en Transplantation et Immunologie (CRTI), UMR1064, INSERM, Université de Nantes, Nantes, France, Institut de Transplantation Urologie Néphrologie (ITUN), CHU Nantes, Nantes, France, LabEx Immunology-Graft-Oncology (IGO), Nantes, France, Institut Hospitalo-Universitaire European Center for Science in Transplantation and Immunology, Nantes, France
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HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition
- Nicolas Jouand,
- Céline Bressollette-Bodin,
- Nathalie Gérard,
- Magali Giral,
- Pierrick Guérif,
- Audrey Rodallec,
- Romain Oger,
- Tiphaine Parrot,
- Mathilde Allard,
- Anne Cesbron-Gautier
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- Published: April 30, 2018
- https://doi.org/10.1371/journal.ppat.1007041