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Open Access
Peer-reviewed
Research Article
HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G
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Terumasa Ikeda,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America, Howard Hughes Medical Institute, University of Minnesota, Minneapolis, Minnesota, United States of America
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Menelaos Symeonides,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliation Cellular, Molecular and Biomedical Sciences Graduate Program and Department of Microbiology and Molecular Genetics, Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, Vermont, United States of America
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John S. Albin,
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliations Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America
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Ming Li,
Roles Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliations Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America
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Markus Thali,
Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliation Cellular, Molecular and Biomedical Sciences Graduate Program and Department of Microbiology and Molecular Genetics, Larner College of Medicine and College of Agriculture and Life Sciences, University of Vermont, Burlington, Vermont, United States of America
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Reuben S. Harris
Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: rsh@umn.edu
Affiliations Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, Minnesota, United States of America, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America, Howard Hughes Medical Institute, University of Minnesota, Minneapolis, Minnesota, United States of America
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HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G
- Terumasa Ikeda,
- Menelaos Symeonides,
- John S. Albin,
- Ming Li,
- Markus Thali,
- Reuben S. Harris
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- Published: April 20, 2018
- https://doi.org/10.1371/journal.ppat.1007010