Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma

• Vandana Sekhar ,

  Contributed equally to this work with: Vandana Sekhar, Teresa Pollicino

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0003-3164-4856

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• Teresa Pollicino ,

  Contributed equally to this work with: Vandana Sekhar, Teresa Pollicino

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliations Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, Division of Clinical and Molecular Hepatology, Department of Human Pathology, University of Messina, Messina, Italy

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• Giacomo Diaz,

  Roles Formal analysis, Writing – original draft

  Affiliation Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

  http://orcid.org/0000-0003-1214-2383

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• Ronald E. Engle,

  Roles Investigation, Writing – original draft

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0003-4174-1983

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• Farah Alayli,

  Roles Investigation, Methodology

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Marta Melis,

  Roles Investigation, Methodology

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Juraj Kabat,

  Roles Data curation, Investigation

  Affiliation Biological Imaging Facility/Research Technologies Branch, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America

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• Ashley Tice,

  Roles Investigation

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0003-1007-1526

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• Anna Pomerenke,

  Roles Investigation

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Nihal Altan-Bonnet,

  Roles Investigation

  Affiliation Laboratory of Host-Pathogen Dynamics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Fausto Zamboni,

  Roles Conceptualization, Data curation

  Affiliation Liver Transplantation Center, Brotzu Hospital, Cagliari, Italy

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• Paolo Lusso,

  Roles Investigation, Writing – review & editing

  Affiliation Viral Pathogenesis Section, Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0002-2813-4081

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• Suzanne U. Emerson,

  Roles Investigation, Writing – review & editing

  Affiliation Molecular Hepatitis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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• Patrizia Farci

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  * E-mail: pfarci@niaid.nih.gov

  Affiliation Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  http://orcid.org/0000-0003-0556-7711

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