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Open Access
Peer-reviewed
Research Article
Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
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P. J. Klasse ,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: jpm2003@med.cornell.edu (JPM); pek2003@med.cornell.edu (PJK)
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Thomas J. Ketas,
Roles Investigation, Methodology
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Christopher A. Cottrell,
Roles Formal analysis, Investigation, Methodology, Visualization
Affiliation Department of Integrative Structural and Computational Biology, IAVI Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America
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Gabriel Ozorowski,
Roles Investigation, Methodology
Affiliation Department of Integrative Structural and Computational Biology, IAVI Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America
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Gargi Debnath,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Diawoye Camara,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Erik Francomano,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Pavel Pugach,
Roles Investigation, Resources
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Rajesh P. Ringe,
Roles Investigation
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Celia C. LaBranche,
Roles Conceptualization, Investigation, Methodology
Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America
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Marit J. van Gils,
Roles Conceptualization, Investigation, Resources, Writing – review & editing
Affiliation Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Christine A. Bricault,
Roles Resources
Affiliation Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
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Dan H. Barouch,
Roles Resources
Affiliation Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America
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Shane Crotty,
Roles Resources
Affiliations Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, California, United States of America, Scripps Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, La Jolla, California, United States of America, School of Medicine, Division of Infectious Diseases, University of California, San Diego, La Jolla, California, United States of America
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Guido Silvestri,
Roles Resources
Affiliations Scripps Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, La Jolla, California, United States of America, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America, Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, United States of America
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Sudhir Kasturi,
Roles Resources
Affiliation Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, United States of America
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Bali Pulendran,
Roles Resources
Current address: Departments of Pathology and of Microbiology, Stanford Medicine, Stanford, California, United States of America
Affiliation Emory Vaccine Center/Yerkes National Primate Research Center at Emory University, Atlanta, Georgia, United States of America
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Ian A. Wilson,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – review & editing
Affiliations Department of Integrative Structural and Computational Biology, IAVI Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, California, United States of America
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David C. Montefiori,
Roles Conceptualization, Investigation, Writing – review & editing
Affiliation Department of Surgery, Duke University Medical Center, Durham, North Carolina, United States of America
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Rogier W. Sanders,
Roles Conceptualization, Funding acquisition, Writing – review & editing
Affiliations Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America, Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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Andrew B. Ward,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Integrative Structural and Computational Biology, IAVI Neutralizing Antibody Center and Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, California, United States of America
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John P. Moore
Roles Conceptualization, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing
* E-mail: jpm2003@med.cornell.edu (JPM); pek2003@med.cornell.edu (PJK)
Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America
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Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
- P. J. Klasse,
- Thomas J. Ketas,
- Christopher A. Cottrell,
- Gabriel Ozorowski,
- Gargi Debnath,
- Diawoye Camara,
- Erik Francomano,
- Pavel Pugach,
- Rajesh P. Ringe,
- Celia C. LaBranche
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- Published: February 23, 2018
- https://doi.org/10.1371/journal.ppat.1006913