Cathepsin B aggravates coxsackievirus B3-induced myocarditis through activating the inflammasome and promoting pyroptosis

• Yaping Wang ,

  Contributed equally to this work with: Yaping Wang, Liangliang Jia

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Liangliang Jia ,

  Contributed equally to this work with: Yaping Wang, Liangliang Jia

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  http://orcid.org/0000-0001-7508-2432

  ⨯
• Jian Shen,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Yidong Wang,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Zurong Fu,

  Roles Data curation, Investigation

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Sheng-an Su,

  Roles Data curation, Investigation

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Zhejun Cai ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: xiangmx@zju.edu.cn (MX); caizhejun@zju.edu.cn (ZC)

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Jian-an Wang,

  Roles Project administration, Resources

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  ⨯
• Meixiang Xiang

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: xiangmx@zju.edu.cn (MX); caizhejun@zju.edu.cn (ZC)

  Affiliation Department of Cardiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Cardiovascular Key Lab of Zhejiang Province, Hangzhou, Zhejiang, China

  http://orcid.org/0000-0002-9634-3088

  ⨯