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Open Access
Peer-reviewed
Research Article
Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs
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Ivan Kosik ,
Contributed equally to this work with: Ivan Kosik, William L. Ince, Lauren E. Gentles
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America
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William L. Ince ,
Contributed equally to this work with: Ivan Kosik, William L. Ince, Lauren E. Gentles
Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing
Affiliations Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America, Center for Drug Evaluation and Research, FDA, Silver Spring, Maryland, United States of America
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Lauren E. Gentles ,
Contributed equally to this work with: Ivan Kosik, William L. Ince, Lauren E. Gentles
Roles Investigation
Affiliation Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America
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Andrew J. Oler,
Roles Methodology, Software, Writing – review & editing
Affiliation Bioinformatics and Computational Biosciences Branch, Office of Cyber Infrastructure and Computational Biology, NIAID, Bethesda, Maryland, United States of America
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Martina Kosikova,
Roles Investigation, Methodology
Affiliation Laboratory of Respiratory Viral Diseases, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America
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Matthew Angel,
Roles Investigation, Software
Affiliation Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America
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Javier G. Magadán,
Roles Investigation
Affiliation Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America
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Hang Xie,
Roles Supervision
Affiliation Laboratory of Respiratory Viral Diseases, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, United States of America
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Christopher B. Brooke ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: cbrooke@illinois.edu (CBB); jyewdell@niaid.nih.gov (JWY)
¶‡ CBB and JWY also contributed equally to this work.
Affiliations Department of Microbiology, School of Molecular and Cellular Biology, University of Illinois, Urbana, Illinois, United States of America, Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, Illinois, United States of America
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Jonathan W. Yewdell
Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing
* E-mail: cbrooke@illinois.edu (CBB); jyewdell@niaid.nih.gov (JWY)
¶‡ CBB and JWY also contributed equally to this work.
Affiliation Cellular Biology Section, Laboratory of Viral Diseases, NIAID, Bethesda, Maryland, United States of America
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Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs
- Ivan Kosik,
- William L. Ince,
- Lauren E. Gentles,
- Andrew J. Oler,
- Martina Kosikova,
- Matthew Angel,
- Javier G. Magadán,
- Hang Xie,
- Christopher B. Brooke,
- Jonathan W. Yewdell
- Published: January 18, 2018
- https://doi.org/10.1371/journal.ppat.1006796