The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types

• Solène Denolly,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation CIRI–International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France

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• Chloé Mialon,

  Roles Formal analysis, Investigation, Methodology

  Affiliation CIRI–International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France

  http://orcid.org/0000-0003-0362-5666

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• Thomas Bourlet,

  Roles Investigation, Methodology

  Affiliation GIMAP, EA 3064, Faculté de Médecine, Université de Saint-Etienne, Univ Lyon, Saint Etienne, France

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• Fouzia Amirache,

  Roles Investigation, Methodology

  Affiliation CIRI–International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France

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• François Penin,

  Roles Formal analysis, Methodology

  Affiliation IBCP—Institut de Biologie et Chimie des Protéines, MMSB, UMR 5086, CNRS, Univ Lyon, Lyon, France

  http://orcid.org/0000-0003-0199-4396

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• Brett Lindenbach,

  Roles Methodology, Resources

  Affiliation Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT, United States of America

  http://orcid.org/0000-0003-4880-1213

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• Bertrand Boson,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation CIRI–International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France

  http://orcid.org/0000-0003-1920-5172

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• François-Loïc Cosset

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: flcosset@ens-lyon.fr

  Affiliation CIRI–International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France

  http://orcid.org/0000-0001-8842-3726

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