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Open Access
Peer-reviewed
Research Article
Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS
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Anjie Zhen ,
Contributed equally to this work with: Anjie Zhen, Christopher W. Peterson
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Christopher W. Peterson ,
Contributed equally to this work with: Anjie Zhen, Christopher W. Peterson
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliations Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Departments of Medicine, University of Washington, Seattle, Washington, United States of America
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Mayra A. Carrillo,
Roles Data curation, Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Sowmya Somashekar Reddy,
Roles Investigation
Affiliation Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
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Cindy S. Youn,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Brianna B. Lam,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Nelson Y. Chang,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Heather A. Martin,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Jonathan W. Rick,
Roles Investigation, Writing – review & editing
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Jennifer Kim,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Nick C. Neel,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Valerie K. Rezek,
Roles Project administration
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Masakazu Kamata,
Roles Investigation
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Irvin S. Y. Chen,
Roles Funding acquisition, Writing – review & editing
Affiliations Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America, Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles, California, United States of America
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Jerome A. Zack,
Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing
Affiliations Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America, Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California, Los Angeles, California, United States of America
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Hans-Peter Kiem,
Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing
Affiliations Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Departments of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Pathology, University of Washington, Seattle, Washington, United States of America
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Scott G. Kitchen
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: skitchen@ucla.edu
Affiliation Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, United States of America
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Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS
- Anjie Zhen,
- Christopher W. Peterson,
- Mayra A. Carrillo,
- Sowmya Somashekar Reddy,
- Cindy S. Youn,
- Brianna B. Lam,
- Nelson Y. Chang,
- Heather A. Martin,
- Jonathan W. Rick,
- Jennifer Kim
![PLOS](/resource/img/logo-plos.png)
- Published: December 28, 2017
- https://doi.org/10.1371/journal.ppat.1006753