miRNA independent hepacivirus variants suggest a strong evolutionary pressure to maintain miR-122 dependence

• Yingpu Yu,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

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• Troels K. H. Scheel,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America, Copenhagen Hepatitis C Program, Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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• Joseph M. Luna,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

  http://orcid.org/0000-0003-2415-9203

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• Hachung Chung,

  Roles Data curation, Writing – original draft

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

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• Eiko Nishiuchi,

  Roles Data curation

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

  http://orcid.org/0000-0003-0107-9614

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• Margaret A. Scull,

  Roles Data curation

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

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• Natalia Echeverría,

  Roles Data curation

  Affiliations Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America, Laboratorio de Virología Molecular, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay

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• Inna Ricardo-Lax,

  Roles Data curation

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

  http://orcid.org/0000-0002-9590-9692

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• Amit Kapoor,

  Roles Conceptualization, Resources

  Affiliations Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, United States of America, Center for Vaccines and Immunity, The Research Institute at Nationwide Children’s Hospital, Columbus, OH, United States of America

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• Ian W. Lipkin,

  Roles Resources

  Affiliation Center for Infection and Immunity, Mailman School of Public Health and College of Physicians & Surgeons, Columbia University, New York, NY, United States of America

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• Thomas J. Divers,

  Roles Resources

  Affiliation Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America

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• Douglas F. Antczak,

  Roles Resources

  Affiliation Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America

  http://orcid.org/0000-0003-3336-5818

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• Bud C. Tennant †,

  † Deceased.

  Roles Resources

  Affiliation Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States of America

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• Charles M. Rice

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ricec@rockefeller.edu

  Affiliation Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY, United States of America

  http://orcid.org/0000-0003-3087-8079

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