HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways

• Fang Guo,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

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• Qiong Zhao,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

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• Muhammad Sheraz,

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization

  Affiliation Microbiology and Immunology graduate program, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America

  http://orcid.org/0000-0003-4780-6581

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• Junjun Cheng,

  Roles Data curation

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

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• Yonghe Qi,

  Roles Data curation

  Affiliation National Institute of Biological Sciences, Beijing, China

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• Qing Su,

  Roles Data curation

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

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• Andrea Cuconati,

  Roles Data curation, Investigation, Resources, Writing – review & editing

  Affiliation Arbutus Biopharma Inc., Doylestown, Pennsylvania, United States of America

  http://orcid.org/0000-0001-5123-0381

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• Lai Wei,

  Roles Resources

  Affiliation Hepatology Institute, Peking University People’s Hospital, Beijing, China

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• Yanming Du,

  Roles Data curation, Resources, Validation

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

  http://orcid.org/0000-0002-4665-8348

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• Wenhui Li,

  Roles Data curation, Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliation National Institute of Biological Sciences, Beijing, China

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• Jinhong Chang ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ju-tao.guo@bblumberg.org (JTG); jinhong.chang@bblumberg.org (JC)

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

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• Ju-Tao Guo

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ju-tao.guo@bblumberg.org (JTG); jinhong.chang@bblumberg.org (JC)

  Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America

  http://orcid.org/0000-0001-5335-2788

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