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Open Access
Peer-reviewed
Research Article
Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis
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Jorge Domínguez-Andrés ,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
* E-mail: jdominguez@cnb.csic.es
Affiliations Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands, Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología/CSIC, Darwin 3, Madrid, Spain
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Rob J. W. Arts,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Rob ter Horst,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Mark S. Gresnigt,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Sanne P. Smeekens,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Jacqueline M. Ratter,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Ekta Lachmandas,
Roles Formal analysis, Investigation
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Lily Boutens,
Roles Formal analysis, Investigation
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Frank L. van de Veerdonk,
Roles Conceptualization, Supervision
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Leo A. B. Joosten,
Roles Conceptualization, Supervision
Affiliation Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands
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Richard A. Notebaart,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Laboratory of Food Microbiology, Wageningen University and Research, Wageningen, The Netherlands
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Carlos Ardavín,
Roles Conceptualization, Funding acquisition, Supervision
Affiliation Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología/CSIC, Darwin 3, Madrid, Spain
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Mihai G. Netea
Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing
Affiliations Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands, Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania
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Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis
- Jorge Domínguez-Andrés,
- Rob J. W. Arts,
- Rob ter Horst,
- Mark S. Gresnigt,
- Sanne P. Smeekens,
- Jacqueline M. Ratter,
- Ekta Lachmandas,
- Lily Boutens,
- Frank L. van de Veerdonk,
- Leo A. B. Joosten
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- Published: September 18, 2017
- https://doi.org/10.1371/journal.ppat.1006632