Binding of a C-type lectin’s coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection

• Jie-Jie Sun ,

  Contributed equally to this work with: Jie-Jie Sun, Jiang-Feng Lan

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong, China

  ⨯
• Jiang-Feng Lan ,

  Contributed equally to this work with: Jie-Jie Sun, Jiang-Feng Lan

  Roles Conceptualization, Data curation, Investigation, Visualization

  Current address: Department of Aquatic Animal Medicine, College of Fisheries, Huazhong Agricultural University, Wuhan, Hubei, China

  Affiliation Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong, China

  ⨯
• Xiao-Fan Zhao,

  Roles Conceptualization, Project administration, Resources, Supervision

  Affiliation Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong, China

  ⨯
• Gerardo R. Vasta,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, School of Medicine, University of Maryland Baltimore and Institute of Marine and Environmental Technology, Baltimore, Maryland, United States of America

  ⨯
• Jin-Xing Wang

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jxwang@sdu.edu.cn

  Affiliation Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Sciences, Shandong University, Jinan, Shandong, China

  http://orcid.org/0000-0003-0283-3930

  ⨯