HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis

Akil Hammami; Belma Melda Abidin; Tania Charpentier; Aymeric Fabié; Annie-Pier Duguay; Krista M. Heinonen; Simona Stäger

doi:10.1371/journal.ppat.1006616

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Open Access

Peer-reviewed

Research Article

HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis

Akil Hammami,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada
⨯
Belma Melda Abidin,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada

http://orcid.org/0000-0002-1406-1344

⨯
Tania Charpentier,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada
⨯
Aymeric Fabié,

Roles Formal analysis, Investigation

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada
⨯
Annie-Pier Duguay,

Roles Formal analysis, Investigation

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada

http://orcid.org/0000-0003-2984-1818

⨯
Krista M. Heinonen,

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Resources, Writing – review & editing

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada
⨯
Simona Stäger

Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft

* E-mail: simona.stager@iaf.inrs.ca

Affiliation INRS-Institut Armand-Frappier and Center for Host-Parasite interactions, 531 Boulevard des Prairies, Laval (QC), Canada

http://orcid.org/0000-0001-5508-9565

⨯

HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis

Akil Hammami,
Belma Melda Abidin,
Tania Charpentier,
Aymeric Fabié,
Annie-Pier Duguay,
Krista M. Heinonen,
Simona Stäger

Published: September 11, 2017
https://doi.org/10.1371/journal.ppat.1006616

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