Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response

• Viktoriya Dubrovskaya,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

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• Javier Guenaga,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation IAVI Neutralizing Center at TSRI, Department of Research and Development, International AIDS Vaccine Initiative, La Jolla, California, United States of America

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• Natalia de Val,

  Roles Formal analysis, Investigation

  Affiliation Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America

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• Richard Wilson,

  Roles Investigation

  Affiliation IAVI Neutralizing Center at TSRI, Department of Research and Development, International AIDS Vaccine Initiative, La Jolla, California, United States of America

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• Yu Feng,

  Roles Investigation

  Affiliation IAVI Neutralizing Center at TSRI, Department of Research and Development, International AIDS Vaccine Initiative, La Jolla, California, United States of America

  http://orcid.org/0000-0003-1564-4098

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• Arlette Movsesyan,

  Roles Investigation

  Affiliation Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America

  http://orcid.org/0000-0001-5601-4100

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• Gunilla B. Karlsson Hedestam,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden

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• Andrew B. Ward,

  Roles Supervision

  Affiliations IAVI Neutralizing Center at TSRI, Department of Research and Development, International AIDS Vaccine Initiative, La Jolla, California, United States of America, Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California, United States of America, The Scripps CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

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• Richard T. Wyatt

  Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: wyatt@scripps.edu

  Affiliations Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, California, United States of America, IAVI Neutralizing Center at TSRI, Department of Research and Development, International AIDS Vaccine Initiative, La Jolla, California, United States of America, The Scripps CHAVI-ID, The Scripps Research Institute, La Jolla, California, United States of America

  http://orcid.org/0000-0001-7085-1351

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