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Open Access
Peer-reviewed
Research Article
Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection
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Yoann Le Breton ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: lebreton@umd.edu (YLB); kmciver@umd.edu (KSM)
Affiliation Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
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Ashton T. Belew,
Roles Data curation, Formal analysis, Software, Visualization, Writing – review & editing
Affiliations Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America
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Jeffrey A. Freiberg,
Roles Investigation, Writing – review & editing
Affiliation Graduate Program in Life Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Ganesh S. Sundar,
Roles Investigation, Validation, Writing – review & editing
Affiliation Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
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Emrul Islam,
Roles Investigation, Validation, Writing – review & editing
Affiliation Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
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Joshua Lieberman,
Roles Investigation, Writing – review & editing
Current address: Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington, United States of America
Affiliation Division of Infectious Diseases, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Mark E. Shirtliff,
Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing
Affiliations Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Department of Microbial Pathogenesis, Dental School, University of Maryland, Baltimore, Maryland, United States of America
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Hervé Tettelin,
Roles Formal analysis, Resources, Writing – review & editing
Affiliations Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America, Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Najib M. El-Sayed,
Roles Data curation, Formal analysis, Funding acquisition, Resources, Writing – review & editing
Affiliations Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America
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Kevin S. McIver
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: lebreton@umd.edu (YLB); kmciver@umd.edu (KSM)
Affiliation Department of Cell Biology & Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
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Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection
- Yoann Le Breton,
- Ashton T. Belew,
- Jeffrey A. Freiberg,
- Ganesh S. Sundar,
- Emrul Islam,
- Joshua Lieberman,
- Mark E. Shirtliff,
- Hervé Tettelin,
- Najib M. El-Sayed,
- Kevin S. McIver
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- Published: August 23, 2017
- https://doi.org/10.1371/journal.ppat.1006584